Спектрофотометрические методы диагностики меланомы кожи. II. Статистические характеристики коэффициентов диффузного отражения

Abstract

Probability density functions of diffuse reflectance values at wavelength 870 nm as well as their mean values and variances for healthy skin, melanoma, and nevus are experimentally found by spectrophotometric means. Malignant transformation risks, diagnostic specificity and sensitivity, and other statistical parameters of the diffuse reflectance are evaluated on the base of the measurements. The spectrophotometric method is shown to provide the maximal methodological validity of more than 0.9 at the threshold reflectance of 0.56. Simultaneously, the first- and second-kind errors are on the order of 0.02 – 0.03, which is practically acceptable for many clinical cases.